This folder contains four directories:

Smodel          --  Contains the basic matlab/sbtoolbox code required 
                    to simulate the Schoeberl model of EGF/ERK 
                    available in the BioModels database. It verifies 
                    the simulation result against a curated set of 
                    published results in the database.

estimation      --  Contains the matlab/sbtoolbox code required to 
                    perform estimation of the rate constants without 
                    using the thermodynamic constraints or by using 
                    TCMC.

makeFinalPlots  --  After the estimated and the TCMC results have been 
                    acquired, the code in this directory can be used to 
                    produce the figures provided in the paper.

JGmodel         --  Matlab file that simulates the EGF/ERK model 
                    obtained by TCMC and compares the results with the 
                    ones produced by the Schroeberl model available in 
                    the BioModels database.
                                      

The BioModels database can be accessed using the following link: 

http://www.ebi.ac.uk/biomodels-main


The Systems Biology Toolbox for Matlab can be accessed using the 
following link: 

http://www.sbtoolbox2.org/main.php